What Is IAC Cleanup?
How the Method Works
The extract passes through the column, the analyte binds to the antibody, interferences are washed away and the analyte is eluted for instrumental analysis.
What IAC Cleanup Detects
Analytes covered by the Fobeventia IAC Cleanup range, grouped by solution.
When Should You Use IAC Cleanup?
IAC Cleanup vs Other Methods
| Requirement | Rapid Test | ELISA | HPLC | LC-MS/MS |
|---|---|---|---|---|
| Speed | ★★★★★ | ★★★★ | ★★ | ★★ |
| Throughput | High | High | Medium | Medium |
| Quantitative | Limited | Yes | Yes | Yes |
| Specificity | - | Good | High | Very High |
| Equipment | Low | Medium | High | Very High |
| Best suited for | Line-side screening | Routine QC | Quantitative analysis | Confirmatory analysis |
Ratings are indicative - validate against your specific analyte and matrix with the Fobeventia technical team.
Unsure which column your process belongs in?
Tell us the analyte, matrix and the decision the result has to support, and a specialist will place it for you.
Solutions Built on IAC Cleanup
IAC Cleanup Products from Fobeventia
IAC cleanupAflatoxin Total Immunoaffinity Column
TypeIAC cleanupApplicationGrains, feed, dairy, spicesView productIAC cleanupAflatoxinB1 Immunoaffinity Column
TypeIAC cleanupApplicationGrains, feed, dairy, spicesView productIAC cleanupAflatoxin M1 Immunoaffinity Column
TypeIAC cleanupApplicationGrains, feed, dairy, spicesView productIAC cleanupOchratoxin A Immunoaffinity Column
TypeIAC cleanupApplicationGrains, feed, dairy, spicesView productIAC cleanupZearalenone Immunoaffinity Column
TypeIAC cleanupApplicationGrains, feed, dairy, spicesView productIAC cleanupDeoxynivalenol Immunoaffinity Column
TypeIAC cleanupApplicationGrains, feed, dairy, spicesView productIAC cleanupFumonisin Immunoaffinity Column
TypeIAC cleanupApplicationGrains, feed, dairy, spicesView productIAC cleanupT-2 Toxin Immunoaffinity Column
TypeIAC cleanupApplicationGrains, feed, dairy, spicesView product
IAC cleanupCitrinin Immunoaffinity Column
TypeIAC cleanupApplicationGrains, feed, dairy, spicesView productLearn More About IAC Cleanup
Frequently Asked Questions
What is IAC Cleanup?
Immunoaffinity columns contain antibodies that selectively bind the target analyte, cleaning up and concentrating the sample extract before HPLC or LC-MS/MS analysis.
What does IAC Cleanup detect?
Fobeventia IAC Cleanup products cover Aflatoxin Total, AflatoxinB1, Aflatoxin M1, Ochratoxin A, Zearalenone, Deoxynivalenol, Fumonisin and T-2 Toxin (and 4 more).
What equipment do I need?
HPLC or LC-MS/MS system, Solvents and consumables and Syringes or a pump manifold; optionally Reference materials and Automation.
Is IAC Cleanup quantitative?
IAC is a sample-preparation step; quantification is done by the instrument that follows.
Which Fobeventia products use IAC Cleanup?
Aflatoxin Total Immunoaffinity Column, AflatoxinB1 Immunoaffinity Column, Aflatoxin M1 Immunoaffinity Column, Ochratoxin A Immunoaffinity Column, Zearalenone Immunoaffinity Column and Deoxynivalenol Immunoaffinity Column (and 8 more).
When should I choose another method?
- Simple matrices may allow direct dilute-and-shoot analysis